-package main
+// Copyright (C) The Lightning Authors. All rights reserved.
+//
+// SPDX-License-Identifier: AGPL-3.0
+
+package lightning
import (
"bytes"
args := []string{"-local=true", "-o=" + libfile[i], "-skip-ooo=true", "-output-tiles", "-tag-library", "testdata/tags"}
if i == 0 {
// ref only
- args = append(args, "-include-no-calls")
+ args = append(args, "-save-incomplete-tiles")
}
args = append(args, infile)
code := (&importer{}).RunCommand("lightning import", args, bytes.NewReader(nil), &bytes.Buffer{}, os.Stderr)
c.Check(statsout.Len() > 0, check.Equals, true)
c.Logf("%s", statsout.String())
- c.Check(ioutil.WriteFile(tmpdir+"/merged.gob", merged.Bytes(), 0666), check.IsNil)
+ err := os.Mkdir(tmpdir+"/merged", 0777)
+ c.Assert(err, check.IsNil)
+ c.Check(ioutil.WriteFile(tmpdir+"/merged/library.gob", merged.Bytes(), 0666), check.IsNil)
- hgvsout := &bytes.Buffer{}
- code = (&exporter{}).RunCommand("lightning export", []string{"-local", "-ref", "testdata/ref.fasta", "-output-format", "hgvs", "-i", tmpdir + "/merged.gob"}, bytes.NewReader(nil), hgvsout, os.Stderr)
+ code = (&exporter{}).RunCommand("lightning export", []string{"-local", "-ref", "testdata/ref.fasta", "-output-format", "hgvs", "-input-dir", tmpdir + "/merged", "-output-dir", tmpdir, "-output-per-chromosome=false"}, bytes.NewReader(nil), os.Stderr, os.Stderr)
c.Check(code, check.Equals, 0)
- c.Check(hgvsout.Len() > 0, check.Equals, true)
- c.Logf("%s", hgvsout.String())
- c.Check(hgvsout.String(), check.Equals, `chr1:g.1_3delinsGGC .
-chr1:g.[41_42delinsAA];[41=] .
-chr1:g.[161=];[161A>T] .
-chr1:g.[178=];[178A>T] .
-chr1:g.222_224del .
+ hgvsout, err := ioutil.ReadFile(tmpdir + "/out.tsv")
+ c.Check(err, check.IsNil)
+ c.Check(sortLines(string(hgvsout)), check.Equals, sortLines(`chr1:g.1_3delinsGGC N
+chr1:g.[41T>A];[41=] N
+chr1:g.[42T>A];[42=] N
+chr1:g.[161=];[161A>T] N
+chr1:g.[178=];[178A>T] N
+chr1:g.222_224del N
chr1:g.[302=];[302_305delinsAAAA] .
. chr2:g.[1=];[1_3delinsAAA]
. chr2:g.125_127delinsAAA
chr2:g.[241_254del];[241=] .
chr2:g.[258_269delinsAA];[258=] .
chr2:g.[315C>A];[315=] .
-chr2:g.[470_472del];[470=] .
-chr2:g.[471=];[471_472delinsAA] .
-`)
+chr2:g.[469_471del];[469=] .
+chr2:g.[471=];[471G>A] .
+chr2:g.[472=];[472G>A] .
+`))
- vcfout := &bytes.Buffer{}
- code = (&exporter{}).RunCommand("lightning export", []string{"-local", "-ref", "testdata/ref.fasta", "-output-format", "vcf", "-i", tmpdir + "/merged.gob", "-output-bed", tmpdir + "/export.bed"}, bytes.NewReader(nil), vcfout, os.Stderr)
+ code = (&exporter{}).RunCommand("lightning export", []string{"-local", "-ref", "testdata/ref.fasta", "-output-dir", tmpdir, "-output-format", "pvcf", "-input-dir", tmpdir + "/merged", "-output-bed", tmpdir + "/export.bed", "-output-per-chromosome=false"}, bytes.NewReader(nil), os.Stderr, os.Stderr)
c.Check(code, check.Equals, 0)
- c.Check(vcfout.Len() > 0, check.Equals, true)
- c.Logf("%s", vcfout.String())
- c.Check(vcfout.String(), check.Equals, `chr1 1 NNN GGC 1/1 0/0
-chr1 41 TT AA 1/0 0/0
-chr1 161 A T 0/1 0/0
-chr1 178 A T 0/1 0/0
-chr1 221 TCCA T 1/1 0/0
-chr1 302 TTTT AAAA 0/1 0/0
-chr2 1 TTT AAA 0/0 0/1
-chr2 125 CTT AAA 0/0 1/1
-chr2 240 ATTTTTCTTGCTCTC A 1/0 0/0
-chr2 258 CCTTGTATTTTT AA 1/0 0/0
-chr2 315 C A 1/0 0/0
-chr2 469 GTGG G 1/0 0/0
-chr2 471 GG AA 0/1 0/0
-`)
+ vcfout, err := ioutil.ReadFile(tmpdir + "/out.vcf")
+ c.Check(err, check.IsNil)
+ c.Check(sortLines(string(vcfout)), check.Equals, sortLines(`##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">
+#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT testdata/pipeline1/input1.1.fasta testdata/pipeline1/input2.1.fasta
+chr1 1 . NNN GGC . . . GT 1/1 0/0
+chr1 41 . T A . . . GT 1/0 0/0
+chr1 42 . T A . . . GT 1/0 0/0
+chr1 161 . A T . . . GT 0/1 0/0
+chr1 178 . A T . . . GT 0/1 0/0
+chr1 221 . TCCA T . . . GT 1/1 0/0
+chr1 302 . TTTT AAAA . . . GT 0/1 0/0
+chr2 1 . TTT AAA . . . GT 0/0 0/1
+chr2 125 . CTT AAA . . . GT 0/0 1/1
+chr2 240 . ATTTTTCTTGCTCTC A . . . GT 1/0 0/0
+chr2 258 . CCTTGTATTTTT AA . . . GT 1/0 0/0
+chr2 315 . C A . . . GT 1/0 0/0
+chr2 468 . CGTG C . . . GT 1/0 0/0
+chr2 471 . G A . . . GT 0/1 0/0
+chr2 472 . G A . . . GT 0/1 0/0
+`))
bedout, err := ioutil.ReadFile(tmpdir + "/export.bed")
c.Check(err, check.IsNil)
c.Logf("%s", string(bedout))
- c.Check(string(bedout), check.Equals, `chr1 0 248 0 500 . 0 224
+ c.Check(sortLines(string(bedout)), check.Equals, sortLines(`chr1 0 248 0 1000 . 0 224
chr1 224 372 1 1000 . 248 348
chr1 348 496 2 1000 . 372 472
chr1 472 572 3 1000 . 496 572
chr2 224 372 5 750 . 248 348
chr2 348 496 6 1000 . 372 472
chr2 472 572 7 1000 . 496 572
-`)
+`))
annotateout := &bytes.Buffer{}
- code = (&annotatecmd{}).RunCommand("lightning annotate", []string{"-local", "-variant-hash=true", "-i", tmpdir + "/merged.gob"}, bytes.NewReader(nil), annotateout, os.Stderr)
+ code = (&annotatecmd{}).RunCommand("lightning annotate", []string{"-local", "-variant-hash=true", "-i", tmpdir + "/merged/library.gob"}, bytes.NewReader(nil), annotateout, os.Stderr)
c.Check(code, check.Equals, 0)
c.Check(annotateout.Len() > 0, check.Equals, true)
sorted := sortLines(annotateout.String())
c.Logf("%s", sorted)
- c.Check(sorted, check.Equals, sortLines(`0 8d4fe9a63921b testdata/ref.fasta chr1:g.161A>T
-0 8d4fe9a63921b testdata/ref.fasta chr1:g.178A>T
-0 8d4fe9a63921b testdata/ref.fasta chr1:g.1_3delinsGGC
-0 8d4fe9a63921b testdata/ref.fasta chr1:g.222_224del
-0 ba4263ca4199c testdata/ref.fasta chr1:g.1_3delinsGGC
-0 ba4263ca4199c testdata/ref.fasta chr1:g.222_224del
-0 ba4263ca4199c testdata/ref.fasta chr1:g.41_42delinsAA
-1 139890345dbb8 testdata/ref.fasta chr1:g.302_305delinsAAAA
-4 cbfca15d241d3 testdata/ref.fasta chr2:g.125_127delinsAAA
-4 cbfca15d241d3 testdata/ref.fasta chr2:g.1_3delinsAAA
-4 f5fafe9450b02 testdata/ref.fasta chr2:g.241_245delinsAAAAA
-4 f5fafe9450b02 testdata/ref.fasta chr2:g.291C>A
-4 fe9a71a42adb4 testdata/ref.fasta chr2:g.125_127delinsAAA
-6 e36dce85efbef testdata/ref.fasta chr2:g.471_472delinsAA
-6 f81388b184f4a testdata/ref.fasta chr2:g.470_472del
+ c.Check(sorted, check.Equals, sortLines(`0,0,8d4fe9a63921b,chr1:g.161A>T
+0,0,8d4fe9a63921b,chr1:g.178A>T
+0,0,8d4fe9a63921b,chr1:g.1_3delinsGGC
+0,0,8d4fe9a63921b,chr1:g.222_224del
+0,0,ba4263ca4199c,chr1:g.1_3delinsGGC
+0,0,ba4263ca4199c,chr1:g.222_224del
+0,0,ba4263ca4199c,chr1:g.41T>A
+0,0,ba4263ca4199c,chr1:g.42T>A
+1,1,139890345dbb8,chr1:g.302_305delinsAAAA
+4,4,cbfca15d241d3,chr2:g.125_127delinsAAA
+4,4,cbfca15d241d3,chr2:g.1_3delinsAAA
+4,4,f5fafe9450b02,chr2:g.241_245delinsAAAAA
+4,4,f5fafe9450b02,chr2:g.291C>A
+4,4,fe9a71a42adb4,chr2:g.125_127delinsAAA
+6,6,e36dce85efbef,chr2:g.471G>A
+6,6,e36dce85efbef,chr2:g.472G>A
+6,6,f81388b184f4a,chr2:g.469_471del
`))
}
projects / lightning.git / blobdiff