"bytes"
"io/ioutil"
"os"
+ "os/exec"
+ "github.com/kshedden/gonpy"
"gopkg.in/check.v1"
)
"-ref=testdata/ref.fasta",
}, &buffer, os.Stderr, os.Stderr)
c.Check(exited, check.Equals, 0)
- output, err := ioutil.ReadFile(tmpdir + "/out.chr1.csv")
- c.Check(err, check.IsNil)
+ output, err := ioutil.ReadFile(tmpdir + "/out.chr1.tsv")
+ if !c.Check(err, check.IsNil) {
+ out, _ := exec.Command("find", tmpdir, "-ls").CombinedOutput()
+ c.Logf("%s", out)
+ }
c.Check(sortLines(string(output)), check.Equals, sortLines(`chr1.1_3delinsGGC 1 0
chr1.41_42delinsAA 1 0
chr1.161A>T 1 0
chr1.222_224del 1 0
chr1.302_305delinsAAAA 1 0
`))
- output, err = ioutil.ReadFile(tmpdir + "/out.chr2.csv")
+ output, err = ioutil.ReadFile(tmpdir + "/out.chr2.tsv")
c.Check(err, check.IsNil)
c.Check(sortLines(string(output)), check.Equals, sortLines(`chr2.1_3delinsAAA 0 1
chr2.125_127delinsAAA 0 1
`))
labels, err := ioutil.ReadFile(tmpdir + "/labels.csv")
c.Check(err, check.IsNil)
- c.Check(string(labels), check.Equals, `0,"input1","out.csv"
-1,"input2","out.csv"
+ c.Check(string(labels), check.Equals, `0,"input1","out.tsv"
+1,"input2","out.tsv"
`)
+ exited = (&exporter{}).RunCommand("export", []string{
+ "-local=true",
+ "-input-dir=" + tmpdir,
+ "-output-dir=" + tmpdir,
+ "-output-format=pvcf",
+ "-ref=testdata/ref.fasta",
+ }, &buffer, os.Stderr, os.Stderr)
+ c.Check(exited, check.Equals, 0)
+ output, err = ioutil.ReadFile(tmpdir + "/out.chr1.vcf")
+ c.Check(err, check.IsNil)
+ c.Log(string(output))
+ c.Check(sortLines(string(output)), check.Equals, sortLines(`##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">
+#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT testdata/pipeline1/input1.1.fasta testdata/pipeline1/input2.1.fasta
+chr1 1 . NNN GGC . . . GT 1/1 0/0
+chr1 41 . TT AA . . . GT 1/0 0/0
+chr1 161 . A T . . . GT 0/1 0/0
+chr1 178 . A T . . . GT 0/1 0/0
+chr1 221 . TCCA T . . . GT 1/1 0/0
+chr1 302 . TTTT AAAA . . . GT 0/1 0/0
+`))
+ output, err = ioutil.ReadFile(tmpdir + "/out.chr2.vcf")
+ c.Check(err, check.IsNil)
+ c.Log(string(output))
+ c.Check(sortLines(string(output)), check.Equals, sortLines(`##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">
+#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT testdata/pipeline1/input1.1.fasta testdata/pipeline1/input2.1.fasta
+chr2 1 . TTT AAA . . . GT 0/0 0/1
+chr2 125 . CTT AAA . . . GT 0/0 1/1
+chr2 240 . ATTTTTCTTGCTCTC A . . . GT 1/0 0/0
+chr2 258 . CCTTGTATTTTT AA . . . GT 1/0 0/0
+chr2 315 . C A . . . GT 1/0 0/0
+chr2 469 . GTGG G . . . GT 1/0 0/0
+chr2 471 . GG AA . . . GT 0/1 0/0
+`))
+
exited = (&exporter{}).RunCommand("export", []string{
"-local=true",
"-input-dir=" + tmpdir,
output, err = ioutil.ReadFile(tmpdir + "/out.chr1.vcf")
c.Check(err, check.IsNil)
c.Log(string(output))
- c.Check(sortLines(string(output)), check.Equals, sortLines(`chr1 1 NNN GGC 1/1 0/0
-chr1 41 TT AA 1/0 0/0
-chr1 161 A T 0/1 0/0
-chr1 178 A T 0/1 0/0
-chr1 221 TCCA T 1/1 0/0
-chr1 302 TTTT AAAA 0/1 0/0
+ c.Check(sortLines(string(output)), check.Equals, sortLines(`#CHROM POS ID REF ALT QUAL FILTER INFO
+chr1 1 . NNN GGC . . AC=2
+chr1 41 . TT AA . . AC=1
+chr1 161 . A T . . AC=1
+chr1 178 . A T . . AC=1
+chr1 221 . TCCA T . . AC=2
+chr1 302 . TTTT AAAA . . AC=1
`))
output, err = ioutil.ReadFile(tmpdir + "/out.chr2.vcf")
c.Check(err, check.IsNil)
c.Log(string(output))
- c.Check(sortLines(string(output)), check.Equals, sortLines(`chr2 1 TTT AAA 0/0 0/1
-chr2 125 CTT AAA 0/0 1/1
-chr2 240 ATTTTTCTTGCTCTC A 1/0 0/0
-chr2 258 CCTTGTATTTTT AA 1/0 0/0
-chr2 315 C A 1/0 0/0
-chr2 469 GTGG G 1/0 0/0
-chr2 471 GG AA 0/1 0/0
+ c.Check(sortLines(string(output)), check.Equals, sortLines(`#CHROM POS ID REF ALT QUAL FILTER INFO
+chr2 1 . TTT AAA . . AC=1
+chr2 125 . CTT AAA . . AC=2
+chr2 240 . ATTTTTCTTGCTCTC A . . AC=1
+chr2 258 . CCTTGTATTTTT AA . . AC=1
+chr2 315 . C A . . AC=1
+chr2 469 . GTGG G . . AC=1
+chr2 471 . GG AA . . AC=1
`))
+
+ outdir := c.MkDir()
+ exited = (&exporter{}).RunCommand("export", []string{
+ "-local=true",
+ "-input-dir=" + tmpdir,
+ "-output-dir=" + outdir,
+ "-output-format=hgvs-numpy",
+ "-ref=testdata/ref.fasta",
+ }, &buffer, os.Stderr, os.Stderr)
+ c.Check(exited, check.Equals, 0)
+
+ f, err := os.Open(outdir + "/matrix.chr1.npy")
+ c.Assert(err, check.IsNil)
+ defer f.Close()
+ npy, err := gonpy.NewReader(f)
+ c.Assert(err, check.IsNil)
+ variants, err := npy.GetInt8()
+ c.Assert(err, check.IsNil)
+ c.Check(variants, check.HasLen, 6*2*2) // 6 variants * 2 alleles * 2 genomes
+ c.Check(variants, check.DeepEquals, []int8{
+ 1, 0, 0, 1, 0, 1, 0, 1, 1, 0, 0, 1, // input1.1.fasta
+ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, // input2.1.fasta
+ })
+
+ f, err = os.Open(outdir + "/matrix.chr2.npy")
+ c.Assert(err, check.IsNil)
+ defer f.Close()
+ npy, err = gonpy.NewReader(f)
+ c.Assert(err, check.IsNil)
+ variants, err = npy.GetInt8()
+ c.Assert(err, check.IsNil)
+ c.Check(variants, check.HasLen, 7*2*2) // 6 variants * 2 alleles * 2 genomes
+ c.Check(variants, check.DeepEquals, []int8{
+ 0, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 1, 0, 1, // input1.1.fasta
+ 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, // input2.1.fasta
+ })
+
+ annotations, err := ioutil.ReadFile(outdir + "/annotations.chr1.csv")
+ c.Check(err, check.IsNil)
+ c.Logf("%s", string(annotations))
+ c.Check(string(annotations), check.Equals, `0,"chr1.1_3delinsGGC"
+1,"chr1.41_42delinsAA"
+2,"chr1.161A>T"
+3,"chr1.178A>T"
+4,"chr1.222_224del"
+5,"chr1.302_305delinsAAAA"
+`)
+ annotations, err = ioutil.ReadFile(outdir + "/annotations.chr2.csv")
+ c.Check(err, check.IsNil)
+ c.Check(string(annotations), check.Equals, `0,"chr2.1_3delinsAAA"
+1,"chr2.125_127delinsAAA"
+2,"chr2.241_254del"
+3,"chr2.258_269delinsAA"
+4,"chr2.315C>A"
+5,"chr2.470_472del"
+6,"chr2.471_472delinsAA"
+`)
}
projects / lightning.git / blobdiff