--- layout: default navsection: userguide title: Welcome to Arvados™! ... _If you are new to Arvados, please try the Quickstart on the documentation homepage instead of this detailed User Guide._ This guide provides a reference for using Arvados to solve big data bioinformatics problems, including: * Robust storage of very large files, such as whole genome sequences, using the "Arvados Keep":{{site.baseurl}}/user/tutorials/tutorial-keep.html content-addressable cluster file system. * Running compute-intensive genomic analysis pipelines, such as alignment and variant calls using the "Arvados Crunch":{{site.baseurl}}/user/tutorials/intro-crunch.html cluster compute engine. * Storing and querying metadata about genome sequence files, such as human subjects and their phenotypic traits using the "Arvados Metadata Database.":{{site.baseurl}}/user/topics/tutorial-trait-search.html * Accessing, organizing, and sharing data, pipelines and results using the "Arvados Workbench":{{site.baseurl}}/user/getting_started/workbench.html web application. The examples in this guide use the public Arvados instance located at {{site.arvados_workbench_host}}. If you are using a different Arvados instance replace @{{ site.arvados_workbench_host }}@ with your private instance in all of the examples in this guide. h2. Typographic conventions This manual uses the following typographic conventions: